Education Archive

HPV testing with p16 triage could be the way forward

That''s the conclusion from a substudy of the NTCC HPV screening trial in this week''s The Lancet Oncology.

It is accepted that HPV testing lacks the specificity of cytology, leading some to suggest that HPV screening and cytology triage provides the best combination of sensitivity and specificity for cervical screening.

This study puts the cat among the pigeons by suggesting that p16 triage following a positive test for high risk HPV might be the best combination, apparently leaving no place for cytology.